“There are no safe paths… Remember you are over the Edge of the Wild now” (Tolkien) This quote from The Hobbit so beautifully encapsulates venture-backed startups. Here’s a bunch of reasons “there are no safe paths…” For your startup to be venture backable, we need to believe it could change…

Here’s 7 things I wish I’d known when I was applying… It took ten years from the time I hoped to become a venture capital investor until the time I actually became one. Ten long years of hanging by the hoops, trying to crack in, a VC desperado. It’s a…

We’re excited to bring new talent into our team at Main Sequence Ventures. We’re looking for a new principal and a new associate. Finding you is the most important thing we’re going to do this year. Here’s some stuff we’d love to learn about you… #What do you care about deeply? What is the impact you want to have in the world? And how can we give you the best opportunity to bring that to life? Tell us where you think we should be investing and why. It’s okay not to land things perfectly. …

Here’s an excerpt from our December 2020 investor report: “You’re on mute” was all too often the way we began our conversations in recent months, virtual calls having become our default, rather than alternate, reality. What were we ‘unmuting’ to talk about? Science of course! Hardly surprising for us deep…